Tissue-Specific Estrogen Action Novel Mechanisms, Novel Ligands, Novel Therapies /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Korach, K. S. (Επιμελητής έκδοσης), Wintermantel, T. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2007.
• Σειρά: Ernst Schering Foundation Symposium Proceedings, 2006/1
• Θέματα: Medicine.; Human physiology.; Molecular biology.; Pharmacology.; Gynecology.; Endocrinology.; Medical biochemistry.; Biomedicine.; Human Physiology.; Medical Biochemistry.; Molecular Medicine.; Pharmacology/Toxicology.

Nuclear hormone receptors are not only important drug targets, but have also been the focus of decades of active and highly insightful research. Ten years ago, a review on nuclear receptors was entitled “The Second Decade” and a special issue of Molecular Endocrinology in 2005 dealt with the results...

Πίνακας περιεχομένων:

• Interfering with the Dynamics of Estrogen Receptor-Regulated Transcription
• Actions of Estrogen and Estrogen Receptors in Nonclassical Target Tissues
• Genetic Dissection of Estrogen Receptor Signaling In Vivo
• Of Mice and Men: The Many Guises of Estrogens
• Estradiol Action in Atherosclerosis and Reendothelialization
• Functional Effects and Molecular Mechanisms of Subtype-Selective ER? and ER? Agonists in the Cardiovascular System
• Pathogenesis and Therapy of Rheumatoid Arthritis
• The Role of ER? and ER? in theProstate: Insights from Genetic Models and Isoform-Selective Ligands
• Preclinical Characterization of Selective Estrogen Receptor ? Agonists: New Insights into Their Therapeutic Potential
• Exploiting Nongenomic Estrogen Receptor-Mediated Signaling for the Development of Pathway-Selective Estrogen Receptor Ligands.