Handbook on Analyzing Human Genetic Data Computational Approaches and Software /

• Main Authors: Lin, Shili (Author), Zhao, Hongyu (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2010.
• Subjects: Medicine.; Human genetics.; Bioinformatics.; Life sciences.; Biomathematics.; Statistics.; Biomedicine.; Human Genetics.; Life Sciences, general.; Statistics for Life Sciences, Medicine, Health Sciences.; Computational Biology/Bioinformatics.; Genetics and Population Dynamics.

The discipline of statistical genetics is highly computational. Be it exact computational methods, simulation based, or a hybrid of the two, computational packages are indispensable tools and constant companions of researchers in the field. This handbook is intended to provide human geneticists and...

Table of Contents:

• Population Genetics
• Haplotype Structure
• Linkage Analysis of Qualitative Traits
• Linkage Analysis of Quantitative Traits
• Markov Chain Monte Carlo Linkage Analysis Methods
• Population-Based Association Studies
• Family-Based Association Studies
• Haplotype Association Analysis
• Multiple Comparisons/Testing Issues
• Estimating the Absolute Risk of Disease Associated with Identified Mutations
• Processing Large-Scale, High-Dimension Genetic and Gene Expression Data.