Molecular Genetics of Recombination

• Corporate Author: SpringerLink (Online service)
• Other Authors: Aguilera, Andrés (Editor), Rothstein, Rodney (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2007.
• Series: Topics in Current Genetics, 17
• Subjects: Life sciences.; Biochemistry.; Cell biology.; Microbial genetics.; Microbial genomics.; Plant genetics.; Animal genetics.; Life Sciences.; Cell Biology.; Biochemistry, general.; Microbial Genetics and Genomics.; Plant Genetics & Genomics.; Animal Genetics and Genomics.

Genetic recombination is an important process involved in shaping the genetic make up of progeny. Increasingly, it has become evident that recombination is a DNA repair pathway crucial during DNA replication in vegetatively growing cells. It plays a critical role in preserving the integrity of the g...

Table of Contents:

• Genetics of Recombination in the Model Bacterium Escherichia Coli
• Homologous Recombination in Low dC + dG Gram-Positive Bacteria
• The Bacterial RecA Protein: Structure, Function, and Regulation
• Biochemistry of Eukaryotic Homologous Recombination
• DNA helicases in recombination
• Holliday Junction Resolution
• Replication forks and replication checkpoints in repair
• Sister chromatid recombination
• Mating-Type Switching in S. Pombe
• Multiple Mechanisms of Repairing Meganuclease-Induced Double-Strand DNA Breaks in Budding Yeast
• The Cell Biology of Mitotic Recombination in Saccharomyces Cerevisiae
• The cell biology of homologous recombination
• BRCA2: safeguarding the genome through homologous recombination
• Meiotic recombination
• Site-specific recombination
• V(D)J Recombination: Mechanism and Consequences
• Nonhomologous End-Joining: Mechanisms, Conservation and Relationship to Illegitimate Recombination
• Analytical methods from the perspective of method standardization.