Progestins and the Mammary Gland From Basic Science to Clinical Applications /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Conneely, O. (Επιμελητής έκδοσης), Otto, C. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.
• Σειρά: Ernst Schering Foundation Symposium Proceedings, 2007/1
• Θέματα: Life sciences.; Molecular biology.; Pharmacology.; Endocrinology.; Reproductive medicine.; Animal genetics.; Life Sciences.; Animal Genetics and Genomics.; Reproductive Medicine.; Molecular Medicine.; Pharmacology/Toxicology.
• Φυσική περιγραφή: XVII, 199 p. online resource.
• ISBN: 9783540734932
• ISSN: 0947-6075 ;

Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed.