Control of Biofilm Infections by Signal Manipulation

• Corporate Author: SpringerLink (Online service)
• Other Authors: Balaban, Naomi (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.
• Series: Springer Series on Biofilms, 2
• Subjects: Medicine.; Infectious diseases.; Proteomics.; Bioinformatics.; Cell biology.; Microbiology.; Bacteriology.; Medicine & Public Health.; Infectious Diseases.; Cell Biology.

The medical miracle of antibiotics is being eroded by the emergence and spread of bacterial drug resistance. This is compounded by the fact that bacterial biofilms are believed to be a common cause of persistent infections, when because growing in biofilms, bacteria are protected from the host’s imm...

Table of Contents:

• Bacterial Cell-to-cell Communication (Quorum Sensing)
• Detection In Vitro of Quorum-Sensing Molecules and Their Inhibitors
• Quorum-Sensing Inhibitory Compounds
• Mathematical Modeling of Quorum-Sensing Control in Biofilms
• Animal Models Commonly Used to Study Quorum-Sensing Inhibitors
• In Vivo Studies: Inhibiting Biofilm-Associated Bacterial Infections Using QSIs
• Quorum Sensing in Streptococci
• Ironing Out the Biofilm Problem:The Role of Iron in Biofilm Formation
• Clinical Wound Healing Using Signal Inhibitors.