Metabolomics A Powerful Tool in Systems Biology /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Nielsen, Jens (Editor), Jewett, Michael C. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2007.
• Series: Topics in Current Genetics, 18
• Subjects: Life sciences.; Biochemistry.; Bioinformatics.; Computational biology.; Microbial genetics.; Microbial genomics.; Biology > Technique.; Life Sciences.; Biochemistry, general.; Biological Techniques.; Microbial Genetics and Genomics.; Computer Appl. in Life Sciences.

The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated to a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the m...

Table of Contents:

• The role of metabolomics in systems biology
• Analytical methods from the perspective of method standardization
• Reporting standards
• The Golm Metabolome Database: a database for GC-MS based metabolite profiling
• Reconstruction of dynamic network models from metabolite measurements
• Toward metabolome-based 13C flux analysis: a universal tool for measuring in vivo metabolic activity
• Data acquisition, analysis, and mining: Integrative tools for discerning metabolic function in Saccharomyces cerevisiae
• E. coli metabolomics: capturing the complexity of a “simple” model
• The exo-metabolome in filamentous fungi
• The importance of anatomy and physiology in plant metabolomics.