Pharmacology of Neurotransmitter Release

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Südhof, Thomas C. (Επιμελητής έκδοσης), Starke, Klaus (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.
• Σειρά: Handbook of Experimental Pharmacology, 184
• Θέματα: Medicine.; Human physiology.; Neurosciences.; Pharmacology.; Neurology.; Biomedicine.; Pharmacology/Toxicology.; Human Physiology.

It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This inc...

Πίνακας περιεχομένων:

• Neurotransmitter Release
• Pharmacology of Neurotransmitter Release: Measuring Exocytosis
• Presynaptic Calcium Channels: Structure, Regulators, and Blockers
• Pharmacology of Neurotransmitter Transport into Secretory Vesicles
• Core Proteins of the Secretory Machinery
• Presynaptic Neurotoxins with Enzymatic Activities
• ?-Latrotoxin and Its Receptors
• Presynaptic Signaling by Heterotrimeric G-Proteins
• Presynaptic Metabotropic Receptors for Acetylcholine and Adrenaline/Noradrenaline
• Presynaptic Receptors for Dopamine, Histamine, and Serotonin
• Presynaptic Adenosine and P2Y Receptors
• Presynaptic Metabotropic Glutamate and GABA B Receptors
• Presynaptic Neuropeptide Receptors
• Presynaptic Modulation by Endocannabinoids
• Presynaptic lonotropic Receptors
• NO/cGMP-Dependent Modulation of Synaptic Transmission
• Therapeutic Use of Release-Modifying Drugs.