Humanized Mice

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Nomura, Tatsuji (Επιμελητής έκδοσης), Watanabe, Takeshi (Επιμελητής έκδοσης), Habu, Sonoko (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.
• Σειρά: Current Topics in Microbiology and Immunology, 324
• Θέματα: Medicine.; Human genetics.; Human physiology.; Immunology.; Biomedicine.; Human Genetics.; Human Physiology.

The term humanized mouse in this text refers to a mouse in which human tissues and cells have been transplanted and show the same biological function as they do in the human body. That is, the physiological properties and functions of tra- planted human tissues and cells can be analyzed in the mouse...

Πίνακας περιεχομένων:

• Basic Concept of Development and Practical Application of Animal Models for Human Diseases
• Humanized SCID Mouse Models for Biomedical Research
• NOD/Shi-scid IL2r?null (NOG) Mice More Appropriate for Humanized Mouse Models
• Humanizing Bone Marrow in Immune-Deficient Mice
• The Differentiative and Regenerative Properties of Human Hematopoietic Stem/Progenitor cells in NOD-SCID/IL2r?null Mice
• Antigen-Specific Antibody Production of Human B Cells in NOG Mice Reconstituted with the Human Immune System
• Humanized Immune System (HIS) Mice as a Tool to Study Human NK Cell Development
• Human T Cell Development and HIV Infection in Human Hemato-Lymphoid System Mice
• Humanized Mice for Human Retrovirus Infection
• Functional and Phenotypic Characterization of the Humanized BLT Mouse Model
• Novel Metastasis Models of Human Cancer in NOG Mice
• In Vivo Imaging in Humanized Mice.