Synaptic Plasticity and the Mechanism of Alzheimer's Disease

• Corporate Author: SpringerLink (Online service)
• Other Authors: Selkoe, Dennis J. (Editor), Triller, Antoine (Editor), Christen, Yves (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.
• Series: Research and Perspectives in Alzheimer's Disease,
• Subjects: Medicine.; Human physiology.; Neurosciences.; Biomedicine.; Human Physiology.

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Table of Contents:

• Permanence of the Synapse and Molecular Instability
• Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity
• Imaging of Experience-Dependent Structural Plasticity in the Mouse Neocortex in vivo
• Synapse Loss, Synaptic Plasticity and the Postsynaptic Density
• Impact of Beta Amyloid on Excitatory Synaptic Transmission and Plasticity
• Quantitative Neuropathology in Alzheimer’s Mouse Models
• Multiple Levels of Synaptic Regulation by NMDA-type Glutamate Receptor in Normal and Disease States
• Soluble Oligomers of the Amyloid ?-Protein: Impair Synaptic Plasticity and Behavior
• Why Alzheimer’s is a Disease of Memory: Synaptic Targeting by Pathogenic A? Oligomers (ADDLs)
• Synaptic Transmission Dynamically Modulates Interstitial Fluid Amyloid-? Levels
• A?-Induced Toxicity Mediated by Caspase Cleavage of the Amyloid Precursor Protein (APP)
• Long-Term Potentiation and A?: Targeting A? Species, Cellular Mechanisms and Putative Receptors
• Genes, Synapses and Autism Spectrum Disorders.