Orphan G Protein-Coupled Receptors and Novel Neuropeptides

• Corporate Author: SpringerLink (Online service)
• Other Authors: Civelli, Olivier (Editor), Zhou, Qun-Yong (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.
• Series: Results and Problems in Cell Differentiation, 46
• Subjects: Life sciences.; Neurosciences.; Pharmacology.; Endocrinology.; Cell biology.; Neurobiology.; Life Sciences.; Pharmacology/Toxicology.; Cell Biology.

Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physi...

Table of Contents:

• The Orphanin FQ/Nociceptin (OFQ/N) System
• Orexins and Orexin Receptors: From Molecules to Integrative Physiology
• Prolactin-Releasing Peptide
• Structure and Function of Ghrelin
• GPR54 and Kisspeptins
• Neuropeptide S: Anatomy, Pharmacology, Genetics and Physiological Functions
• The Melanin-Concentrating Hormone System and Its Physiological Functions
• Biological Function of Prokineticins
• Neuromedin S: Discovery and Functions
• Relaxin-3, INSL5, and Their Receptors
• The NPB/NPW Neuropeptide System and Its Role in Regulating Energy Homeostasis, Pain, and Emotion.