Diverse Roles of Integrin Receptors in Articular Cartilage

• Main Authors: Shakibaei, Mehdi (Author), Csaki, Constanze (Author), Mobasheri, Ali (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.
• Series: Advances in Anatomy Embryology and Cell Biology, 197
• Subjects: Medicine.; Biomedicine.; Biomedicine general.

Integrins belong to an evolutionary conserved family of adhesion molecules with important biological functions throughout the animal kingdom. They are heterodimeric glycoproteins involved in cell-cell and cell-matrix adhesion and communication. Physiologically they function as intra- and extracellul...

Table of Contents:

• Introduction
• Integrins - multifunctional adhesion molecules
• Integrin structure-function relationships
• Structure of integrins
• EGF domains in ß1-integrins
• Integrins in articular cartilage
• Monolayer cultures
• High density (organoid-) cultures
• Concluding remarks
• Acknowledgements
• References
• Subject index.