Oncogenes Meet Metabolism From Deregulated Genes to a Broader Understanding of Tumour Physiology /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Kroemer, G. (Editor), Mumberg, D. (Editor), Keun, H. (Editor), Riefke, B. (Editor), Steger-Hartmann, T. (Editor), Petersen, K. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.
• Series: Ernst Schering Foundation Symposium Proceedings, 2007/4
• Subjects: Medicine.; Human physiology.; Analytical chemistry.; Oncology.; Medicine & Public Health.; Human Physiology.; Analytical Chemistry.

In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed...