Oncogenes Meet Metabolism From Deregulated Genes to a Broader Understanding of Tumour Physiology /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Kroemer, G. (Επιμελητής έκδοσης), Mumberg, D. (Επιμελητής έκδοσης), Keun, H. (Επιμελητής έκδοσης), Riefke, B. (Επιμελητής έκδοσης), Steger-Hartmann, T. (Επιμελητής έκδοσης), Petersen, K. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.
• Σειρά: Ernst Schering Foundation Symposium Proceedings, 2007/4
• Θέματα: Medicine.; Human physiology.; Analytical chemistry.; Oncology.; Medicine & Public Health.; Human Physiology.; Analytical Chemistry.

In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed...

Πίνακας περιεχομένων:

• Mitochondria and Cancer
• Role of the Metabolic Stress Responses of Apoptosis and Autophagy in Tumor Suppression
• The Interplay Between MYC and HIF in the Warburg Effect
• Using Metabolomics to Monitor Anticancer Drugs
• Biomarker Discovery for Drug Development and Translational Medicine Using Metabonomics
• Pyruvate Kinase Type M2: A Key Regulator Within the Tumour Metabolome and a Tool for Metabolic Profiling of Tumours
• Molecular Imaging of Tumor Metabolism and Apoptosis
• Minimally Invasive Biomarkers for Therapy Monitoring
• Use of Metabolic Pathway Flux Information in Anticancer Drug Design
• Cancer Diagnostics Using 1H-NMR-Based Metabonomics
• Human Metabolic Phenotyping and Metabolome Wide Association Studies
• Defining Personal Nutrition and Metabolic Health Through Metabonomics.