Pharmacology and Therapeutics of Cough

• Corporate Author: SpringerLink (Online service)
• Other Authors: Chung, Kian Fan (Editor), Widdicombe, John (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2009.
• Series: Handbook of Experimental Pharmacology, 187
• Subjects: Medicine.; Human physiology.; Pharmacology.; Allergy.; Internal medicine.; Gastroenterology.; Respiratory organs > Diseases.; Biomedicine.; Pharmacology/Toxicology.; Human Physiology.; Allergology.; Pneumology/Respiratory System.; Internal Medicine.

The last decade or so has seen remarkable advances in our knowledge of cough. This applies especially to its basic mechanisms: the types of airway sensors, the phar- cological receptors on their membranes, the brainstem organization of the ‘cough centre’, and the involvement of the cerebral cortex i...

Table of Contents:

• Cough: Setting the Scene
• Cough Sensors. I. Physiological and Pharmacological Properties of the Afferent Nerves Regulating Cough
• Cough Sensors. II. Transient Receptor Potential Membrane Receptors on Cough Sensors
• Cough Sensors. III. Opioid and Cannabinoid Receptors on Vagal Sensory Nerves
• Cough Sensors. IV. Nicotinic Membrane Receptors on Cough Sensors
• Cough Sensors. V. Pharmacological Modulation of Cough Sensors
• Peripheral Mechanisms I: Plasticity of Peripheral Pathways
• Peripheral Mechanisms II: The Pharmacology of Peripherally Active Antitussive Drugs
• Central Mechanisms I: Plasticity of Central Pathways
• Central Mechanisms II: Pharmacology of Brainstem Pathways
• Central Mechanisms III: Neuronal Mechanisms of Action of Centrally Acting Antitussives Using Electrophysiological and Neurochemical Study Approaches
• Central Mechanisms IV: Conscious Control of Cough and the Placebo Effect
• Clinical Cough I: The Urge-To-Cough: A Respiratory Sensation
• Clinical Cough II: Therapeutic Treatments and Management of Chronic Cough
• Clinical Cough III: Measuring the Cough Response in the Laboratory
• Clinical Cough IV:What is the Minimal Important Difference for the Leicester Cough Questionnaire?
• Clinical Cough V: Complementary and Alternative Medicine: Therapy of Cough
• Clinical Cough VI: The Need for New Therapies for Cough: Disease-Specific and Symptom-Related Antitussives.