The Ubiquitin System in Health and Disease

• Corporate Author: SpringerLink (Online service)
• Other Authors: Jentsch, S. (Editor), Haendler, B. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2009.
• Series: Ernst Schering Foundation Symposium Proceedings, 2008/1
• Subjects: Medicine.; Medical biochemistry.; Medicine & Public Health.; Medical Biochemistry.; Biomedicine general.; Medicine/Public Health, general.

Table of Contents:

• Crosstalk Between the SUMO and Ubiquitin Pathways
• A Tale of Two Giant Proteases
• Molecular Genetics of the Ubiquitin-Proteasome System: Lessons from Yeast
• Less Is More: How Protein Degradation Regulates Muscle Development
• Transcriptional Control and the Ubiquitin–Proteasome System
• Ubiquitination of Myc: Proteasomal Degradation and Beyond
• Regulation of Apoptosis and Cytokinesis by the Anti-apoptotic E2/E3 Ubiquitin-Ligase BRUCE
• Dissecting Roles of Ubiquitination in the p53 Pathway
• Regulation of T Cell Differentiation and Allergic Responses by the E3 Ubiquitin Ligase Itch
• Approaches to Discovering Drugs that Regulate E3 Ubiquitin Ligases
• Inhibiting Hdm2 and Ubiquitin-Activating Enzyme: Targeting the Ubiquitin Conjugating System in Cancer.