Cholera Toxins

• Corporate Author: SpringerLink (Online service)
• Other Authors: Chaudhuri, Keya (Editor), Chatterjee, S. N. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2009.
• Subjects: Medicine.; Medical microbiology.; Pharmacology.; Food > Biotechnology.; Biochemistry.; Cell biology.; Microbiology.; Biomedicine.; Medical Microbiology.; Food Science.; Biochemistry, general.; Cell Biology.; Pharmacology/Toxicology.

Vibrio cholerae, the causative organism of the disease Cholera, colonizes the small intestine and produces several different toxins among which the enterotoxin, or more widely known as cholera toxin (CT), happens to be the major virulence determinant that is responsible for the diarrheal syndrome. T...

Table of Contents:

• An Introduction to Cholera
• Bacterial Toxins: A Brief Overview
• Vibrio cholerae, the Causative Organism
• Endotoxin of Vibrio cholerae: Physical and Chemical Characterization
• Endotoxin of Vibrio cholerae: Genetics of Biosynthesis
• Endotoxin of Vibrio cholerae: Biological Functions
• Cholera Toxin (CT): Structure
• Cholera Toxin (CT): Organization and Function of the Relevant Genetic Elements
• Cholera Toxin (CT): Regulation of the Relevant Virulence Genes
• Cholera Toxin (CT): Secretion by the Vibrios
• Cholera Toxin (CT): Entry and Retrograde Trafficking into the Epithelial Cell
• Cholera Toxin (CT): Immune Response of the Host and Vaccine Production
• Other Toxins of Vibrio cholerae
• Concluding Notes.