Lead-Seeking Approaches

• Corporate Author: SpringerLink (Online service)
• Other Authors: Hayward, Matthew M. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2010.
• Series: Topics in Medicinal Chemistry, 5
• Subjects: Chemistry.; Neurosciences.; Organic chemistry.; Medicinal chemistry.; Medicinal Chemistry.; Organic Chemistry.

Christopher A. Lipinski: Overview of Hit to Lead: The Medicinal Chemist’s Role from HTS Retest to Lead Optimization Hand Off Jeff W. Paslay • John E. Morin • Richard K. Harrison: High Throughput Screening in the Twenty - First Century Jack Andrew Bikker • Lakshmi S.Narasimhan: Lead Discovery Using V...

Table of Contents:

• Hit Triage: Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery
• Lead Identification
• Lead Discovery Using Virtual Screening
• Overview of Hit to Lead: The Medicinal Chemist's Role from HTS Retest to Lead Optimization Hand Off
• NMR Spectroscopy in Fragment Based Drug Design
• High Throughput Screening in the Twenty-First Century.