Death Receptors and Cognate Ligands in Cancer

Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by co...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Kalthoff, Holger (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2009.
Σειρά:Results and Problems in Cell Differentiation, 49
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • The Role of TNF in Cancer
  • Many Checkpoints on the Road to Cell Death:Regulation of Fas–FasL Interactions and Fas Signaling in Peripheral Immune Responses
  • FasL Expression and Reverse Signalling
  • Impact of TNF-R1 and CD95 Internalization on Apoptotic and Antiapoptotic Signaling
  • Ubiquitination and TNFR1 Signaling
  • From Biochemical Principles of Apoptosis Induction by TRAIL to Application in Tumour Therapy
  • Therapeutic Targeting of TWEAK/Fn14 in Cancer: Exploiting the Intrinsic Tumor Cell Killing Capacity of the Pathway
  • APRIL in B-cell Malignancies and Autoimmunity
  • Autophagy in Cancer and Chemotherapy
  • Glucocorticoid-Mediated Apoptosis Resistance of Solid Tumors
  • Targeting Death-Receptors in Radiation Therapy
  • Death Ligands Designed to Kill: Development and Application of Targeted Cancer Therapeutics Based on Proapoptotic TNF Family Ligands.