Death Receptors and Cognate Ligands in Cancer
Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by co...
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg,
2009.
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| Series: | Results and Problems in Cell Differentiation,
49 |
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| Online Access: | Full Text via HEAL-Link |
Table of Contents:
- The Role of TNF in Cancer
- Many Checkpoints on the Road to Cell Death:Regulation of Fas–FasL Interactions and Fas Signaling in Peripheral Immune Responses
- FasL Expression and Reverse Signalling
- Impact of TNF-R1 and CD95 Internalization on Apoptotic and Antiapoptotic Signaling
- Ubiquitination and TNFR1 Signaling
- From Biochemical Principles of Apoptosis Induction by TRAIL to Application in Tumour Therapy
- Therapeutic Targeting of TWEAK/Fn14 in Cancer: Exploiting the Intrinsic Tumor Cell Killing Capacity of the Pathway
- APRIL in B-cell Malignancies and Autoimmunity
- Autophagy in Cancer and Chemotherapy
- Glucocorticoid-Mediated Apoptosis Resistance of Solid Tumors
- Targeting Death-Receptors in Radiation Therapy
- Death Ligands Designed to Kill: Development and Application of Targeted Cancer Therapeutics Based on Proapoptotic TNF Family Ligands.
