Laron Syndrome - From Man to Mouse Lessons from Clinical and Experimental Experience /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Laron, Zvi (Επιμελητής έκδοσης), Kopchick, J. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2011.
• Θέματα: Medicine.; Human genetics.; Human physiology.; Molecular biology.; Internal medicine.; Endocrinology.; Pediatrics.; Medicine & Public Health.; Internal Medicine.; Human Genetics.; Molecular Medicine.; Human Physiology.

Laron syndrome (LS), or primary growth hormone (GH) insensitivity, was first described in 1966. Since then, many patients worldwide have been diagnosed with LS, which involves defects in the GH receptor that cause combined congenital deficiency of GH and IGF-I activities. In this comprehensive book...

Πίνακας περιεχομένων:

• From the Content: Part I - Laron Syndrome in Man
• Clinical Aspects
• History of the Israeli Cohort of Laron Syndrome Patients
• Early Investigations
• Clinical Evidence of Growth Hormone Resistance in Patients with Laron Syndrome
• Diagnosis of Laron Syndrome
• Genetic Aspects
• Clinical Evaluation
• Perinatal Evaluation
• Perinatal Development ;Laron Syndrome
• Linear Growth Pattern of Untreated Laron Syndrome Patients
• Head Shape, Size and Growth of Untreated Patients with Laron Syndrome
• Sexual Development in Patients with Laron Syndrome.