Medicinal Organometallic Chemistry

• Corporate Author: SpringerLink (Online service)
• Other Authors: Jaouen, Gérard (Editor), Metzler-Nolte, Nils (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2010.
• Series: Topics in Organometallic Chemistry, 32
• Subjects: Chemistry.; Cancer research.; Pharmaceutical technology.; Biochemical engineering.; Organometallic chemistry.; Medicinal chemistry.; Organometallic Chemistry.; Medicinal Chemistry.; Cancer Research.; Pharmaceutical Sciences/Technology.; Biochemical Engineering.
• Physical Description: XVIII, 294 p. 179 illus., 11 illus. in color. online resource.
• ISBN: 9783642131851
• ISSN: 1436-6002 ;

Contents: Gérard Jaouen, Nils Metzler-Nolte : Introduction ; Stéphane GIBAUD and Gérard JAOUEN: Arsenic - based drugs: from Fowler’s solution to modern anticancer chemotherapy; Ana M. Pizarro, Abraha Habtemariam and Peter J. Sadler : Activation Mechanisms for Organometallic Anticancer Complexes; Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson : Organometallic antitumour agents with alternative modes of action; Elizabeth A. Hillard, Anne Vessières, Gerard Jaouen : Ferrocene functionalized endocrine modulators for the treatment of cancer; Megan Hogan and Matthias Tacke : Titanocenes – Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer; Seann P. Mulcahy and Eric Meggers : Organometallics as Structural Scaffolds for Enzyme Inhibitor Design; Christophe Biot and Daniel Dive : Bioorganometallic Chemistry and Malaria; Nils Metzler-Nolte : Biomedical applications of organometal-peptide conjugates; Roger Alberto : Organometallic Radiopharmaceuticals; Brian E. Mann : Carbon Monoxide – an essential signaling molecule.