Diverse Effects of Hypoxia on Tumor Progression

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Simon, M. Celeste (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2010.
• Σειρά: Current Topics in Microbiology and Immunology, 345
• Θέματα: Medicine.; Cancer research.; Human physiology.; Embryology.; Biomedicine.; Cancer Research.; Human Physiology.

Solid tumors frequently contain areas of oxygen deprivation (hypoxia) due to rapid cell proliferation and/or vascular insufficiency. The presence of hypoxic domains typically correlates with poor patient prognosis, due to the relative resistance of hypoxic cells to conventional cancer therapies and...

Πίνακας περιεχομένων:

• The HIF-2?-Driven Pseudo-Hypoxic Phenotype in Tumor Aggressiveness, Differentiation, and Vascularization
• Hypoxia and Hypoxia Inducible Factors in Cancer Stem Cell Maintenance
• Role of Carcinoma-Associated Fibroblasts and Hypoxia in Tumor Progression
• The Role of Hypoxia Regulated microRNAs in Cancer
• Oxygen Sensing: A Common Crossroad in Cancer and Neurodegeneration
• Hypoxia-Inducible Factors as Essential Regulators of Inflammation
• Hypoxia and Metastasis in Breast Cancer.