The Role of Model Integration in Complex Systems Modelling An Example from Cancer Biology /

• Main Authors: Patel, Manish (Author), Nagl, Sylvia (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2010.
• Series: Understanding Complex Systems,
• Subjects: Engineering.; Cancer research.; Systems biology.; Statistical physics.; Dynamical systems.; Complexity, Computational.; Complexity.; Statistical Physics, Dynamical Systems and Complexity.; Systems Biology.; Cancer Research.

Model integration – the process by which different modelling efforts can be brought together to simulate the target system – is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth lite...

Table of Contents:

• Nature to Numbers: Complex Systems Modelling of Cancer
• Coping with Complexity: Modelling of Complex Systems
• Complexity and Model Integration: Formalisations
• Novel Strategies for Integrating Models into Systems-Level Simulations
• Experiments in Model Integration
• Discussion.