Behavioral Neurobiology of Bipolar Disorder and its Treatment

• Corporate Author: SpringerLink (Online service)
• Other Authors: Manji, Husseini K. (Editor), Zarate Jr., Carlos A. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2011.
• Series: Current Topics in Behavioral Neurosciences, 5
• Subjects: Medicine.; Human genetics.; Neurosciences.; Radiology.; Psychiatry.; Psychopharmacology.; Biomedicine.; Human Genetics.; Imaging / Radiology.

Despite the devastating impact of bipolar disorder on the lives of millions worldwide, many aspects of its underlying etiology and pathophysiology remain unknown. This book, which has assembled a widely respected group of preclinical and clinical researchers, acts as a valuable and timely resource f...

Table of Contents:

• From the contents
• Preface
• Course and Outcome of Bipolar Disorder
• Genetics of Bipolar Disorder
• Epigenetic factors in Bipolar Disorder
• Clinical Endophenotypes in Bipolar Disorder
• Animal Models for the Study of Bipolar Disorder: Endophenotype and Lesion-Based Models
• Animal Models for the Study of Bipolar Disorder: Genetic-Based Models
• The Role of the –aminergic Systems in the Pathophysiology of Bipolar Disorder
• The Role of the GABAergic and Glutamatergic Systems in the Pathophysiology of Bipolar Disorder
• The Role of Signal Transduction Pathways in the Pathophysiology of Bipolar Disorder
• The Role of Synaptic and Neural Plasticity in the Pathophysiology of Bipolar Disorder
• Mitochondrial Dysfunction and Bipolar Disorder
• Structural Neuroimaging and Neuropathological Findings in Bipolar Disorder
• Functional Neuroimaging Findings in Bipolar Disorder: A Developmental Perspective
• Sleep and Biological Rhythm Abnormalities in the Pathophysiology of Bipolar Disorder.