NF-kB in Health and Disease

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Karin, Michael (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2011.
• Σειρά: Current Topics in Microbiology and Immunology, 349
• Θέματα: Medicine.; Cancer research.; Biomedicine.; Cancer Research.

This volume is focused on a transcription factor that started its life as a B cell-specific nuclear protein, but has matured to become one of the most extensively studied transcriptional regulators, found to control many pathophysiological processes: NF-kB. Articles in the volume, all of them writte...

Πίνακας περιεχομένων:

• Preface
• Understanding the Logic of IkappaB:NF-kappaB Regulation in Structural Terms
• IKK regulation and human genetics
• Specialized chromatin patterns in the control of inflammatory gene expression
• Macrophages and NF-kappaB in Cancer
• NF-κB/Rel proteins and the humoral immune responses of Drosophila melanogaster
• IKK and NF-kappaB mediated functions in carcinogenesis
• Control of NF-kappaB activity by proteolysis
• NF-kappaB as a target for oncogenic viruses
• NF-kappaB and Innate Immunity
• Inhibition of NF-kappaB signaling as a strategy in disease therapy
• NF-κB and mucosal homeostasis
• NF-kappaB In liver cancer – the plot thickens
• Subject index.