Extracellular Matrix Degradation

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Parks, William C. (Επιμελητής έκδοσης), Mecham, Robert P. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2011.
• Σειρά: Biology of Extracellular Matrix ; 2
• Θέματα: Life sciences.; Molecular biology.; Biochemistry.; Proteins.; Cell biology.; Life Sciences.; Cell Biology.; Biochemistry, general.; Protein Science.; Molecular Medicine.

Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Bi...

Πίνακας περιεχομένων:

• Matrix Metalloproteinases and Their Inhibitors in Turnover and Degradation of Extracellular Matrix
• Role of Cysteine Cathepsins in Extracellular Proteolysis
• Cooperation between proteolysis and endocytosis in collagen turnover
• Pericellular Proteolysis
• Triple Helicase Activity and the Structural Basis of Collagenolysis
• Structural Basis of Extracellular Matrix Interactions with Matrix Metalloproteinases
• The Role of Matrix Metalloproteinases in Cellular Invasion and Metastasis
• Degradation of bone and the role of osteoclasts, bone lining cells and osteocytes
• Consequences of Elastolysis.