Small-Molecule Inhibitors of Protein-Protein Interactions

• Corporate Author: SpringerLink (Online service)
• Other Authors: Vassilev, Lyubomir (Editor), Fry, David (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2011.
• Series: Current Topics in Microbiology and Immunology, 348
• Subjects: Medicine.; Biomedicine.; Biomedicine general.

body> In this volume, the editors have collected the knowledgeable insights of a number of leaders in this field - researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions. These researchers describe their unique approaches, and share ex...

Table of Contents:

• Preface
• Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions
• Small-molecule inhibitors of IL-2/IL-2R: lessons learned and applied
• Small Molecule Inhibitors of the Human Papillomavirus E1-E2 Interaction
• Design of small-molecule Smac mimetics as IAP antagonists
• Small-molecule inhibitors reveal a new function for Bcl-2 as a pro-angiogenic signaling molecule
• Small-molecule modulators of c-Myc/Max and Max/Max interactions.-  Small-molecule inhibitors of the p53-MDM2 interaction
• Subject index.