Sensing the Environment: Regulation of Local and Global Homeostasis by the Skin's Neuroendocrine System

• Main Authors: Slominski, Andrzej T. (Author), Zmijewski, Michal A. (Author), Skobowiat, Cezary (Author), Zbytek, Blazej (Author), Slominski, Radomir M. (Author), Steketee, Jeffery D. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2012.
• Series: Advances in Anatomy, Embryology and Cell Biology, 212
• Subjects: Medicine.; Neurosciences.; Dermatology.; Biomedicine.

The skin, the body’s largest organ, is strategically located at the interface with the external environment where it detects, integrates and responds to a diverse range of stressors, including solar radiation. It has already been established that the skin is an important peripheral neuroendocrine-im...

Table of Contents:

• Introduction
• Biogenic amines in the skin
• Melatoninergic system in the skin
• Cutaneous cholinergic system
• Corticotropin signaling system in the skin
• Steroidogenesis in the skin
• Equivalent of hypothalamo-pituitary adrenal axis in the skin
• Cutaneous secosteroidal system
• Equivalent of hypthalamic-pituitary-thyroid axis
• Cutaneous opioid system
• Cutaneous endocannabinoid system
• Perspectives
• References
• Subject index.