Ribonucleases

• Corporate Author: SpringerLink (Online service)
• Other Authors: Nicholson, Allen W. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2011.
• Series: Nucleic Acids and Molecular Biology,
• Subjects: Life sciences.; Molecular biology.; Nucleic acids.; Enzymology.; Cell biology.; Life Sciences.; Nucleic Acid Chemistry.; Cell Biology.; Molecular Medicine.

Ribonucleases are a ubiquitous and functionally diverse group of enzymes that have a common ability to cleave RNA. Either through scission of internal phosphodiesters, or removal of nucleotides from RNA 5’ or 3’ ends, ribonucleases perform essential roles in gene expression and regulation, genome re...

Table of Contents:

• The Superfamily of Vertebrate Secreted Ribonucleases
• Vertebrate Secretory (RNase A) Ribonucleases and Host Defense
• Antitumor Ribonucleases
• RNase T2 family: enzymatic properties, functional diversity, and evolution of ancient ribonucleases
• Stress-induced Ribonucleases
• Viral RNase Involvement in Strategies of Infection
• 5’-3’ exoribonucleases
• Structure and degradation mechanisms of 3’ to 5’ exoribonucleases
• The RNA exosomes
• The Metallo--Lactamase Family of Ribonucleases
• Ribonuclease III and the Role of Double-Stranded RNA Processing in Bacterial Systems
• Structure and function of RNase H enzymes
• Ribonucleoprotein Ribonucleases P and MRP
• Nonenzymatic and Metal-ion-dependent RNA Cleavage, and RNase Models
• Ribonucleases as Models for Understanding Protein Folding.