Modeling Fragile X Syndrome

The present book is an in-depth synopsis of recent advances in the fragile X field. The fragile X syndrome (FXS) is the most common form of inherited mental retardation, and the molecular-genetic basis of this syndrome has been the subject of extensive experimental scrutiny over the last two decades...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Denman, Robert B. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2012.
Σειρά:Results and Problems in Cell Differentiation, 54
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Introduction: Reminiscing on Models and Modeling
  • Probing Astrocyte Function in Fragile X Syndrome
  • Neural Stem Cells
  • Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System
  • The role of the postsynaptic density in the pathology of the fragile X syndrome
  • Behavior in a Drosophila model of Fragile X
  • Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome
  • Fragile X Mental Retardation Protein and Stem Cells
  • Manipulating the Fragile Mental Retardation Proteins in the frog
  • Exploring the zebra finch Taeniopygia guttata as a novel animal model for the speech-language deficit of fragile X syndrome
  • Neuroendocrine alterations in the fragile X mouse
  • Taking STEPs forward to understanding Fragile X Syndrome
  • Fmr-1 as an offspring genetic and a maternal environmental factor in neurodevelopmental disease
  • Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome
  • Clinical Aspects of the Fragile X Syndrome
  • Fragile X Syndrome: A Psychiatric Perspective
  • Fragile X Syndrome and Targeted Treatment Trials
  • The Fragile X-associated Tremor Ataxia Syndrome
  • Vignettes: Models in Absentia.