Ricin and Shiga Toxins Pathogenesis, Immunity, Vaccines and Therapeutics /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Mantis, Nicholas (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2012.
• Σειρά: Current Topics in Microbiology and Immunology, 357
• Θέματα: Medicine.; Pharmacology.; Biomedicine.; Pharmacology/Toxicology.

The intent of this volume of Current Topics in Microbiology and Immunology was to bring together a collection of in-depth and cutting edge reviews that highlight our current understanding of the biology of ricin and Shiga toxin (Stx), with the long term goal of advancing the development of counterme...

Πίνακας περιεχομένων:

• Preface
• Interaction of ricin and Stx with ribosomes and the sarcin-ricin loop
• How ricin and Stx enter and intoxicate mammalian cells
• Cellular stress response to Stx-ricin
• Ricin and Stx-Inflammation
• Pathogenesis of shiga-toxin producing E.coli
• Ricin and Stx-Interactions with the epithelium and intestinal mucosa
• Stx Pathogenesis-Kidney complications and renal failure
• Toxin-induced Apoptosis
• Small Molecule Inhibitors of Ricin and STX
• Antibody-mediated immunity to ricin
• Stx-animal models and immunotherapies
• Ricin- animal models and immunotherapies
• Ricin Vaccine Development
• Subject Index.