Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer

Most deaths from carcinomas are caused by the hematogenous dissemination of cancer cells to distant organs and the eventual development of metastases. When found in the bone marrow or peripheral blood of carcinoma patients, occult cancer cells are referred to as disseminated tumor cells (DTCs) or ci...

Full description

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Ignatiadis, Michail (Editor), Sotiriou, Christos (Editor), Pantel, Klaus (Editor)
Format: Electronic eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2012.
Series:Recent Results in Cancer Research, 195
Subjects:
Online Access:Full Text via HEAL-Link
LEADER 03203nam a22005415i 4500
001 978-3-642-28160-0
003 DE-He213
005 20151204163417.0
007 cr nn 008mamaa
008 120420s2012 gw | s |||| 0|eng d
020 |a 9783642281600  |9 978-3-642-28160-0 
024 7 |a 10.1007/978-3-642-28160-0  |2 doi 
040 |d GrThAP 
050 4 |a RC254-282 
072 7 |a MJCL  |2 bicssc 
072 7 |a MED062000  |2 bisacsh 
082 0 4 |a 616.994  |2 23 
245 1 0 |a Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer  |h [electronic resource] /  |c edited by Michail Ignatiadis, Christos Sotiriou, Klaus Pantel. 
264 1 |a Berlin, Heidelberg :  |b Springer Berlin Heidelberg,  |c 2012. 
300 |a XIV, 254 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Recent Results in Cancer Research,  |x 0080-0015 ;  |v 195 
520 |a Most deaths from carcinomas are caused by the hematogenous dissemination of cancer cells to distant organs and the eventual development of metastases. When found in the bone marrow or peripheral blood of carcinoma patients, occult cancer cells are referred to as disseminated tumor cells (DTCs) or circulating tumor cells (CTCs). CTCs and DTCs are considered surrogates of minimal residual disease, i.e., the presence of malignant cells in distant organs that are undetectable by conventional imaging and laboratory tests used for tumor staging after curative surgery of the primary tumor.   In this book, leading investigators in the field provide up-to-date information on a series of important questions, including:   -  How can the study of minimal residual disease and CTCs help us to better understand breast cancer metastasis? -  What technologies are available for the detection and characterization of CTCs and DTCs, and what are their relative merits? -  How are DTCs and CTCs relevant to clinical research and practice? - What is the role of other blood-based biomarkers such as circulating endothelial cells and circulating nucleic acids? -  What are the challenges in drug and biomarker co-development and the use of CTCs for companion diagnostic development?   This book will be of interest and assistance to all who are engaged in the modern management of breast cancer. 
650 0 |a Medicine. 
650 0 |a Cancer research. 
650 0 |a Gynecology. 
650 0 |a Oncology. 
650 0 |a Pathology. 
650 0 |a Surgical oncology. 
650 1 4 |a Medicine & Public Health. 
650 2 4 |a Oncology. 
650 2 4 |a Gynecology. 
650 2 4 |a Surgical Oncology. 
650 2 4 |a Pathology. 
650 2 4 |a Cancer Research. 
700 1 |a Ignatiadis, Michail.  |e editor. 
700 1 |a Sotiriou, Christos.  |e editor. 
700 1 |a Pantel, Klaus.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9783642281594 
830 0 |a Recent Results in Cancer Research,  |x 0080-0015 ;  |v 195 
856 4 0 |u http://dx.doi.org/10.1007/978-3-642-28160-0  |z Full Text via HEAL-Link 
912 |a ZDB-2-SME 
950 |a Medicine (Springer-11650)