Epigenetic Mechanisms in Cellular Reprogramming

• Corporate Author: SpringerLink (Online service)
• Other Authors: Meissner, Alexander (Editor), Walter, Jörn (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2015.
• Series: Epigenetics and Human Health,
• Subjects: Medicine.; Human genetics.; Nucleic acids.; Systems biology.; Cell biology.; Biomedicine.; Human Genetics.; Cell Biology.; Systems Biology.; Nucleic Acid Chemistry.
• Physical Description: XVIII, 230 p. 20 illus., 19 illus. in color. online resource.
• ISBN: 9783642319747
• ISSN: 2191-2262

The ability of a single genome to give rise to hundreds of functionally distinct cell type programs is in itself remarkable. Pioneering studies over the past few decades have demonstrated that this plasticity is retained throughout development, a phenomenon of epigenetic programming and reprogramming that remains one of the most fascinating areas of modern biology, with major relevance to human health and disease. This book presents the basic biology involved, including key mechanistic insights into this rapidly growing field.