CRISPR-Cas Systems RNA-mediated Adaptive Immunity in Bacteria and Archaea /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Barrangou, Rodolphe (Επιμελητής έκδοσης), van der Oost, John (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
• Θέματα: Life sciences.; Medical microbiology.; Microbiology.; Microbial genetics.; Microbial genomics.; Life Sciences.; Microbial Genetics and Genomics.; Medical Microbiology.

CRISPR-Cas is a recently discovered defense system which protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR-Cas immune systems has been identified in at least half of the available prokaryotic genomes. On-going b...

Πίνακας περιεχομένων:

• Discovery and seminal developments in the CRISPR field
• Occurrence, diversity of CRISPR-Cas systems and genotyping implications
•  Evolution and classification of CRISPR-Cas systems and Cas protein families
• Regulation of CRISPR-based immune responses
• crRNA Biogenesis
• Distribution and mechanism of the Type I CRISPR/Cas Systems
• Type II – Streptococcus thermophilus
• Type III CRISPR-Cas Systems and the Roles CRISPR-Cas in Bacterial Virulence
• CRISPR-Cas Systems to Probe Ecological Diversity and Host-Viral Interactions
• Roles of CRISPR in regulation of physiological processes
• Applications of the versatile CRISPR-Cas systems
• CRISPRs in microbial community context.