Programmed Cells from Basic Neuroscience to Therapy

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Gage, Fred H. (Επιμελητής έκδοσης), Christen, Yves (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
• Σειρά: Research and Perspectives in Neurosciences, 20
• Θέματα: Medicine.; Neurosciences.; Neurology.; Stem cells.; Biomedicine.; Stem Cells.

The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed the experimental landscape and opened new possibilities. The advances in PSC have provided an important tool for the study of human neuronal function...

Πίνακας περιεχομένων:

• Nuclear reprogramming by eggs and oocytes and eventual prospects of cell replacement therapy.- iPS technology and disease research: issues to be resolved
• ES and iPS cells as tools for modeling human aging .-Characterizing neural circuitry with programmed human neurons.- Direct conversion of fibroblasts to neuronal cells
• Human pluripotent stem cells as tools for modelling neurodegeneration.- From Rett syndrome to classical autism: modeling autism spectrum disorders using human neurons.- Testing evolutionary principles in a dish using embryonic stem cells: the example of the Huntington's Disease gene.- Using stem cells to discover therapeutic targets in ALS and SMA .- Using stem cells to understand and treat Alzheimer's disease.- Using pluripotent stem cells to decipher mechanisms and identify treatments for diseases that affect the brain.- Modeling neural development and disease in human pluripotent stem cells
• Subject index.