Disruption of Protein-Protein Interfaces In Search of New Inhibitors /

"Disruption of Protein-Protein Interfaces" reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces, as well as including details of experimental and computational tools to tackle the subject, and highlighting the contribution of the Italian r...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Mangani, Stefano (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Drug discovery by targeting protein-protein interactions
  • Protein-Protein Interaction Inhibitors: case studies on small molecules and natural compounds
  • Disrupting Protein-Protein Interfaces using GRID Molecular Interaction Fields
  • NMR as a tool to target protein-protein interactions
  • Protein-protein interactions in the solid state The troubles of crystallizing of protein- protein complexes
  • Fluorescence observables and enzyme kinetics in the investigation of PPI modulation by small molecules Detection, mechanistic insight, functional consequences.