Thymic Development and Selection of T Lymphocytes

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Boehm, Thomas (Επιμελητής έκδοσης), Takahama, Yousuke (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2014.
• Σειρά: Current Topics in Microbiology and Immunology, 373
• Θέματα: Medicine.; Cytogenetics.; Human physiology.; Immunology.; Biomedicine.; Human Physiology.

The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in th...

Πίνακας περιεχομένων:

• Development and Function of Cortical Thymic Epithelial Cells
• Mechanisms of Thymus Medulla Development And Function
• Self-peptides in TCR Repertoire Selection and Peripheral T Cell Function.-  Central Tolerance Induction
• Trafficking to the Thymus
• The CD4/CD8 Lineages: Central Decisions and Peripheral Modifications for T Lymphocytes.