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03359nam a22005055i 4500 |
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978-3-642-40444-3 |
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DE-He213 |
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20151204141204.0 |
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cr nn 008mamaa |
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131018s2014 gw | s |||| 0|eng d |
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|a 9783642404443
|9 978-3-642-40444-3
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|a 10.1007/978-3-642-40444-3
|2 doi
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|a SCI045000
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|a 579
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|a Antimicrobial Compounds
|h [electronic resource] :
|b Current Strategies and New Alternatives /
|c edited by Tomás G. Villa, Patricia Veiga-Crespo.
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| 264 |
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|a Berlin, Heidelberg :
|b Springer Berlin Heidelberg :
|b Imprint: Springer,
|c 2014.
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| 300 |
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|a XVI, 316 p. 47 illus., 18 illus. in color.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
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|a online resource
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|a text file
|b PDF
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|a Strategies for the design and discovery of novel antibiotics using genetic engineering and genome mining -- X-ray and Neutron Scattering Foundations for the Research in Antimicrobials -- Antibacterial, Antiviral and Antifungal Activity of Essential Oils: Mechanisms and Applications -- New antimicrobial agents of plant origin -- Advances in beta-lactam antibiotics -- The Cornerstone of Nucleic Acid-affecting Antibiotics in Bacteria -- Genetic analysis and manipulation of polyene antibiotic gene clusters as a way to produce more effective antifungal compounds -- Enzybiotics: The rush towards prevention and control of multi-resistant bacteria (MRB) -- New cell wall-affecting antifungal antibiotics -- Perspectives in the research on Antimicrobial peptides -- Glycopeptides and bacterial cell walls.
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| 520 |
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|a Since penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years. This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics.
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| 650 |
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|a Life sciences.
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| 650 |
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|a Medical microbiology.
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| 650 |
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|a Pharmaceutical technology.
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| 650 |
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0 |
|a Microbiology.
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| 650 |
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|a Microbial genetics.
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| 650 |
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|a Microbial genomics.
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| 650 |
1 |
4 |
|a Life Sciences.
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| 650 |
2 |
4 |
|a Microbiology.
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| 650 |
2 |
4 |
|a Medical Microbiology.
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| 650 |
2 |
4 |
|a Microbial Genetics and Genomics.
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| 650 |
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4 |
|a Pharmaceutical Sciences/Technology.
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| 700 |
1 |
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|a Villa, Tomás G.
|e editor.
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| 700 |
1 |
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|a Veiga-Crespo, Patricia.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 776 |
0 |
8 |
|i Printed edition:
|z 9783642404436
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| 856 |
4 |
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|u http://dx.doi.org/10.1007/978-3-642-40444-3
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
|
