Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development

• Corporate Author: SpringerLink (Online service)
• Other Authors: Bonifer, Constanze (Editor), Cockerill, Peter N. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2014.
• Series: Epigenetics and Human Health,
• Subjects: Medicine.; Cancer research.; Human genetics.; Biomedicine.; Human Genetics.; Cancer Research.

In recent years, great progress has been made in the identification of the molecular players involved in the epigenetic control of gene expression during development. The work of many laboratories has established that regulating the interplay of transcription factors with chromatin components is the...

Table of Contents:

• Preface
• Introduction
• Non-mammalian hematopoiesis
• Epigenetic mechanisms regulating mammalian hematopoietic stem cell development and function
• Epigenetic and transcriptional mechanisms regulating cell fate decisions and blood cell lineage development
• Epigenetic control of immune cell function
• Subject index.