Treatment–Refractory Schizophrenia A Clinical Conundrum /

Schizophrenia is often associated with an inadequate response to pharmacological and non-pharmacological treatments. How to treat patients who have an unsatisfactory response to anti-psychotics, including clozapine - which is unequivocally the most powerful antipsychotic medication for this recalcit...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Buckley, Peter F. (Editor), Gaughran, Fiona (Editor)
Format: Electronic eBook
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2014.
Subjects:
Online Access:Full Text via HEAL-Link
Table of Contents:
  • Definitions and scope of treatment-refractory schizophrenia
  • Biology of schizophrenia: Is treatment-refractoriness synonymous with severity of illness
  • Evolution of refractoriness
  • Medical and psychiatric comorbidities: Complicating treatment expectations
  • Overview of pharmacologic treatments and guidelines
  • Clozapine: Gold standard treatment for refractory schizophrenia: Now or never
  • Augmenting clozapine and other antipsychotic medications: Pharmacologic choices and differential outcomes
  • Augmenting clozapine therapy: Emerging neuromodulatory strategies
  • Cognitive remediation for refractory schizophrenia
  • Psychological and familial therapies for refractory schizophrenia
  • Vocational performance of patients with chronic schizophrenia
  • Refractory schizophrenia and the criminal justice system: A failure of continuity of care and a real challenge
  • Personalized medicine: A ‘game changer’ in the care of patients with treatment-refractory schizophrenia?