Nucleic Acids in the Gas Phase

• Corporate Author: SpringerLink (Online service)
• Other Authors: Gabelica, Valérie (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2014.
• Series: Physical Chemistry in Action,
• Subjects: Chemistry.; Mass spectrometry.; Spectroscopy.; Bioorganic chemistry.; Physical chemistry.; Nucleic acids.; Biophysics.; Biological physics.; Mass Spectrometry.; Nucleic Acid Chemistry.; Biophysics and Biological Physics.; Spectroscopy/Spectrometry.; Bioorganic Chemistry.; Physical Chemistry.

This book gives physical chemists a broader view of potential biological applications of their techniques for the study of nucleic acids in the gas phase. It provides organic chemists, biophysicists, and pharmacologists with an introduction to new techniques they can use to find the answers to yet u...

Table of Contents:

• Introduction: Why study Nucleic Acids in vacuo?
• Transferring Nucleic Acids to the Gas Phase
• Structure of Nucleic Acids in the Gas Phase
• Interactions between Nucleic Acid Ions and Electrons and Photons
• Gas-phase Spectroscopy of Nucleic Acids
• Fragmentation Reactions of Nucleic Acid Ions in the Gas Phase
• Characterization of Ribonucleic Acids and their Modifications by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
• Quantification of DNA Damage using Mass Spectrometry Techniques
• Ligand Binding to Nucleic Acids
• MS-based Approaches for Nucleic Acid Structural Determination.