Optimized Response-Adaptive Clinical Trials Sequential Treatment Allocation Based on Markov Decision Problems /
Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial desi...
Κύριος συγγραφέας: | |
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Συγγραφή απο Οργανισμό/Αρχή: | |
Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
Γλώσσα: | English |
Έκδοση: |
Wiesbaden :
Springer Fachmedien Wiesbaden : Imprint: Springer Spektrum,
2015.
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Σειρά: | BestMasters
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Θέματα: | |
Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Introduction to Markov Decision Problems and Examples
- Finite and Infinite Horizon Markov Decision Problems
- Solution Algorithms: Backward Induction, Value Iteration and Policy Iteration
- Designing Response Adaptive Clinical Trials with Markov Decision Problems.