Optimized Response-Adaptive Clinical Trials Sequential Treatment Allocation Based on Markov Decision Problems /

Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial desi...

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Κύριος συγγραφέας: Ondra, Thomas (Συγγραφέας)
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Wiesbaden : Springer Fachmedien Wiesbaden : Imprint: Springer Spektrum, 2015.
Σειρά:BestMasters
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Introduction to Markov Decision Problems and Examples
  • Finite and Infinite Horizon Markov Decision Problems
  • Solution Algorithms: Backward Induction, Value Iteration and Policy Iteration
  • Designing Response Adaptive Clinical Trials with Markov Decision Problems.