MicroRNAs in malignant tumors of the skin First steps of tiny players in the skin to a new world of genomic medicine /

• Κύριος συγγραφέας: Sand, PD Dr. Michael (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Wiesbaden : Springer Fachmedien Wiesbaden : Imprint: Springer, 2016.
• Θέματα: Medicine.; Cancer research.; Dermatology.; Pathology.; Medicine & Public Health.; Cancer Research.

Michael Sand gives the reader an overview of current techniques in expression profiling of miRNAs and their maturation machinery in the skin. This book is a postdoctoral thesis on miRNAs in cutaneous malignant melanoma and non-melanoma skin cancer with a focus on the miRNA processing machinery and m...

Πίνακας περιεχομένων:

• Introduction
• Objectives of this work
• Summary and discussion of this work
• Closing remarks
• Paper 1: Expression levels of the microRNA processing enzymes Drosha and Dicer in epithelial skin cancer
• Paper 2: Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA- induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1 and TARBP2 in epithelial skin cancer
• Paper 3: Expression of microRNAs in basal cell carcinoma
• Paper 4: Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma
• Paper 5: The miRNA machinery in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi
• Paper 6: Immunohistochemical expression patterns of the microRNA-processing enzyme Dicer in cutaneous malignant melanomas, benign melanocytic nevi and dysplastic melanocytic nevi
• Paper 7: Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi
• Paper 8: MicroRNAs and the skin: tiny players in the body’s largest organ
• Paper 9: microRNA in non-melanoma skin cancer.