Interleukin-10 in Health and Disease

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Fillatreau, Simon (Επιμελητής έκδοσης), O'Garra, Anne (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2014.
• Σειρά: Current Topics in Microbiology and Immunology, 380
• Θέματα: Medicine.; Immunology.; Molecular biology.; Cytokines.; Growth factors.; Biomedicine.; Cytokines and Growth Factors.; Molecular Medicine.

This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the...

Πίνακας περιεχομένων:

• IL-10 in humans: lessons from the gut, IL-10/IL-10 receptor deficiencies and IL-10 polymorphisms
• Control of intestinal inflammation by interleukin-10
• Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications
• Interleukin-10-producing B cells and the regulation of immunity
• Pathogen Manipulation of cIL-10 Signaling Pathways: Opportunities for Vaccine Development?- IL-10: achieving balance during persistent viral infection
• The role of microRNAs in the control and mechanism of action of IL-10
• The regulation of IL-10 expression
• The Molecular Basis of IL-10 Function: From Receptor Structure to the Onset of Signaling
• Role of IL-22 in microbial host defense.