Pharmacology of Itch

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Cowan, Alan (Επιμελητής έκδοσης), Yosipovitch, Gil (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2015.
• Σειρά: Handbook of Experimental Pharmacology, 226
• Θέματα: Medicine.; Immunology.; Pharmacology.; Allergy.; Anesthesiology.; Dermatology.; Pain medicine.; Biomedicine.; Pharmacology/Toxicology.; Pain Medicine.; Allergology.

Basic research on the pharmacology of itch has exploded in the wake of two very influential papers that were published in Nature (2007) and Science (2009). Long overlooked as a milder form of pain, itching has rapidly gained a new appreciation in both research and clinical communities because of its...

Πίνακας περιεχομένων:

• Historical Background
• Epidemiology of the Burden of Chronic Itch
• Neurophysiology and Itch Pathways
• Brain Mechanisms of Chronic Itch
• Mouse and Human Models of Itch. Transient Receptor Potential Channels and Itch
• Cytokines and Itch
• Role of Mrgpr Family of Receptors and Itch
• Protease-activated Receptor Agonists and Itch
• VGLUT2-dependent Sensory Neurons and Itch
• Identification and Characterization of Spinal Inhibitory Neurons That Inhibit Itch
• Noradrenergic Itch Transmission in the Spinal Cord
• NK-1 Antagonists and Itch
• Cannabinoids and Itch
• Antihistamines and Itch
• Targeting Itch with Ligands Selective for k Opioid Receptors
• Neuraxial Opioid-induced Scratching and Its Pharmacological Antagonism
• Topical Therapies
• Allergic Itch in Dogs.