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03566nam a22004935i 4500 |
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978-3-662-45024-6 |
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DE-He213 |
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20151204143814.0 |
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cr nn 008mamaa |
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141127s2015 gw | s |||| 0|eng d |
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|a 9783662450246
|9 978-3-662-45024-6
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|a 10.1007/978-3-662-45024-6
|2 doi
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|a 615.372
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|a Vaccine Analysis: Strategies, Principles, and Control
|h [electronic resource] /
|c edited by Brian K. Nunnally, Vincent E. Turula, Robert D. Sitrin.
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| 264 |
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1 |
|a Berlin, Heidelberg :
|b Springer Berlin Heidelberg :
|b Imprint: Springer,
|c 2015.
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| 300 |
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|a XII, 665 p. 124 illus., 76 illus. in color.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 347 |
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|a text file
|b PDF
|2 rda
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|a Live Attenuated Viral Vaccines -- Inactivated Viral Vaccines -- Recombinant Virus Like Particle Protein Vaccines -- Analysis of influenza vaccines -- Live-attenuated and inactivated whole-cell bacterial vaccines -- Analytical control strategy of bacterial subunit vaccines -- Bacterial Polysaccharide Vaccines: Analytical Perspectives -- Glycoconjugate vaccines -- Vaccines in research and development: new production platforms and new biomolecular entities for new needs -- Role of Analytics In Viral Safety -- Deep Sequencing Applications for Vaccine Development and Safety -- Quality-by-design: As related to analytical concepts, control and qualification -- Vaccine Potency Assays -- Establishing a Shelf-life and Setting Lot-release Specifications -- Vaccine Reference Standards -- Lot Release of Vaccines by Regulatory Authorities and Harmonization of Testing Requirements -- Dendritic cell targeting vaccines.
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| 520 |
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|a This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.
|
| 650 |
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0 |
|a Medicine.
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| 650 |
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0 |
|a Immunology.
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| 650 |
|
0 |
|a Vaccines.
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| 650 |
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0 |
|a Medical biochemistry.
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| 650 |
1 |
4 |
|a Biomedicine.
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| 650 |
2 |
4 |
|a Vaccine.
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| 650 |
2 |
4 |
|a Immunology.
|
| 650 |
2 |
4 |
|a Medical Biochemistry.
|
| 700 |
1 |
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|a Nunnally, Brian K.
|e editor.
|
| 700 |
1 |
|
|a Turula, Vincent E.
|e editor.
|
| 700 |
1 |
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|a Sitrin, Robert D.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
|
| 773 |
0 |
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|t Springer eBooks
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| 776 |
0 |
8 |
|i Printed edition:
|z 9783662450239
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| 856 |
4 |
0 |
|u http://dx.doi.org/10.1007/978-3-662-45024-6
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
|
