Pain Control

• Corporate Author: SpringerLink (Online service)
• Other Authors: Schaible, Hans-Georg (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2015.
• Series: Handbook of Experimental Pharmacology, 227
• Subjects: Medicine.; Human physiology.; Pharmacology.; Medical biochemistry.; Pain medicine.; Biomedicine.; Pharmacology/Toxicology.; Pain Medicine.; Medical Biochemistry.; Human Physiology.

This volume addresses neuronal pain mechanisms at the peripheral, spinal and supraspinal level which are thought to significantly contribute to pain and which may be the basis for the development of new treatment principles. Chapters on nociceptive mechanisms in the peripheral nociceptive system add...

Table of Contents:

• Emerging concepts of pain therapy based on neuronal mechanisms
• The pharmacology of nociceptor priming
• Sodium channels and pain
• Role of nerve growth factor in pain
• Central sensitization in humans – assessment and pharmacology
• The role of NO in the spinal cord
• The role of the endocannabinoid system in pain
• The role of glia in the spinal cord in neuropathic and inflammatory pain
• Plasticity of inhibition in the spinal cord
• Gene regulation in nociception. Modulation of peripheral inflammation by the spinal cord
• The relationship between opioids and cytokines in the spinal cord
• The role of proteases in pain. Pain-related pharmacology in the amygdala
• Pain and itch – differences and commonalities.