Gene Vaccines

The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion en...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Thalhamer, Josef (Επιμελητής έκδοσης), Weiss, Richard (Επιμελητής έκδοσης), Scheiblhofer, Sandra (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Vienna : Springer Vienna : Imprint: Springer, 2012.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Preface
  • 1 General mechanisms of gene vaccines
  • 2 Strategies to Improve DNA Vaccine Potency: HPV-associated Cervical Cancer as a Model System
  • 3 Immune-activating mechanisms of replicase-based DNA and RNA vaccines and their role in immune-apoptosis
  • 4 Cytokine genes as molecular adjuvants for DNA vaccines
  • 5 Pharmaceutical non-viral formulations for gene vaccines
  • 6 Rational design of formulated DNA vaccines: the DermaVir approach
  • 7 In vivo electroporation
  • 8 Electroporation-based Trigrid™ delivery system (TDS) for DNA vaccine administration
  • 9 Prime Boost Regimens for Enhancing Immunity: Magnitude, Quality of Mucosal and Systemic Gene Vaccines
  • 10 Intranodal genetic immunization
  • 11 Immunotherapy of cancer with RNA vaccines
  • 12 DNA and RNA vaccines for prophylactic and therapeutic treatment of type I allergy
  • 13 Approved veterinary vaccines – paving the way to products for human use
  • 14 Current status of regulations for DNA vaccines
  • 15 State of the art production of antibiotic resistance-free plasmid DNA
  • 16 Industrial Manufacturing of Plasmid-DNA Products for Gene Vaccination and Therapy.  .