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02611nam a22004455i 4500 |
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978-3-7091-0687-7 |
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DE-He213 |
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20150519181800.0 |
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cr nn 008mamaa |
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130913s2014 au | s |||| 0|eng d |
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|a 9783709106877
|9 978-3-7091-0687-7
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|a 10.1007/978-3-7091-0687-7
|2 doi
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|d GrThAP
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|a RC346-429.2
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|a MJN
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|a MED056000
|2 bisacsh
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|a 616.8
|2 23
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|a Multiple System Atrophy
|h [electronic resource] /
|c edited by Gregor K. Wenning, Alessandra Fanciulli.
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| 264 |
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|a Vienna :
|b Springer Vienna :
|b Imprint: Springer,
|c 2014.
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| 300 |
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|a XVI, 198 p. 33 illus., 20 illus. in color.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a text file
|b PDF
|2 rda
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0 |
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|a 1. Historical Review -- 2. Epidemiology -- 3. Neuropathology -- 4. Etiopathogenesis -- 5. Animal Models -- 6. Clinical Presentation -- 7. Clinical diagnostic Criteria -- 8. Natural History -- 9. Investigations -- 10. Tratment.
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|a This textbook provides a comprehensive monography on multiple system atrophy (MSA), a rare and fatal neurodegenerative disorder that presents with autonomic failure and either parkinsonism (MSA-P) or cerebellar ataxia (MSA-C).The underlying neuropathology of MSA is characterized by striatonigral degeneration (SND), olivopontocerebellar atrophy (OPCA) and unique oligodendroglial cytoplasmic alpha-synuclein inclusions. MSA is therefore classified among the alpha-synucleinopathies such as Parkinson`s disease, pure autonomic failure and dementia with Lewy bodies. Over the last decade there have been important advances in early diagnosis, pathogenesis research and clinical trial activity. The monography will cover the entire spectrum ranging from molecular and genetic work to symptomatic and interventional therapies. The book is written for movement disorder clinicians and basic neuroscientists interested in degenerative movement disorders.
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| 650 |
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|a Medicine.
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| 650 |
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|a Neurosciences.
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| 650 |
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|a Neurology.
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| 650 |
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4 |
|a Medicine & Public Health.
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| 650 |
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4 |
|a Neurology.
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| 650 |
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4 |
|a Neurosciences.
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| 700 |
1 |
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|a Wenning, Gregor K.
|e editor.
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| 700 |
1 |
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|a Fanciulli, Alessandra.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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| 776 |
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|i Printed edition:
|z 9783709106860
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|u http://dx.doi.org/10.1007/978-3-7091-0687-7
|z Full Text via HEAL-Link
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| 912 |
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|a ZDB-2-SME
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| 950 |
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|a Medicine (Springer-11650)
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