Jak-Stat Signaling : From Basics to Disease

• Corporate Author: SpringerLink (Online service)
• Other Authors: Decker, Thomas (Editor), Müller, Mathias (Editor)
• Format: Electronic eBook
• Language: English
• Published: Vienna : Springer Vienna : Imprint: Springer, 2012.
• Subjects: Life sciences.; Cancer research.; Medical genetics.; Immunology.; Hematology.; Cell biology.; Stem cells.; Life Sciences.; Stem Cells.; Cell Biology.; Cancer Research.; Gene Function.

JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to environmental cues. The Jak-Stat pathway is involved in the regulation of cell development, differentia...